Timosaponin AIII Suppresses Hepatocyte Growth Factor-Induced Invasive Activity through Sustained ERK Activation in Breast Cancer MDA-MB-231 Cells
Figure 4
Effects of Timosaponin AIII on HGF-induced COX2 gene expression in MDA-MB-231 cells. TAIII concentration dependently (10−8~10−6 M) inhibited HGF-induced COX2 gene expression by Western blot (a, b) and by real-time PCR (c) 24 h and 12 h after drug treatment in MDA-MB-231 cells, respectively. * compared to serum free; # compared to HGF (15 ng/mL) alone-treat group (one-way ANOVA, followed by Dunnett’s test).
