Curcumin Pretreatment Prevents Potassium Dichromate-Induced Hepatotoxicity, Oxidative Stress, Decreased Respiratory Complex I Activity, and Membrane Permeability Transition Pore Opening

Figure 7

Effect of curcumin on the activity of antioxidant enzymes activity in hepatic mitochondria isolated from rats exposed to K₂Cr₂O₇. (a) Superoxide dismutase (SOD), (b) catalase (CAT), (c) glutathione peroxidase (GPx), (d) glutathione reductase (GR), and (e) glutathione-S-transferase (GST). Values are mean ± SEM, 𝑛= 5-6. ^a𝑃<0.05versus control; ^b𝑃<0.05versus K₂Cr₂O₇ (24 h); ^c𝑃<0.05versus K₂Cr₂O₇ (48 h).

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