Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 432829, 7 pages
Research Article

Compounds from the Fruits of the Popular European Medicinal Plant Vitex agnus-castus in Chemoprevention via NADP(H):Quinone Oxidoreductase Type 1 Induction

1State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, The Chinese Academy of Sciences, Kunming, Yunnan 650204, China
2South China Botanical Garden, Chinese Academy of Sciences, 723 Xingke Road, Tianhe District, Guangzhou 510650, China
3Division of Life Science, The Hong Kong University of Science and Technology, Clear Water Bay Road, Hong Kong
4Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 S. Wood Street, Chicago, IL 60612, USA
5School of Chinese Medicine, Hong Kong Baptist University, 7 Baptist University Road, Kowloon Tong, Hong Kong

Received 30 January 2013; Accepted 5 March 2013

Academic Editor: Ludger Beerhues

Copyright © 2013 Shenghong Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. “Delectis Florae Reipublicae Popularis Sinicae Agendae Academiae Sinicae Edita,” in Flora Republicae Popularis Sinicae, vol. 65, pp. 131–150, Science Press, Beijing, 1982.
  2. S. H. Li, Studies on the chemical and biological constituents of three Taxaceae plants, Vitex agnus-castus and Isodon xerophilus [Ph.D. thesis], Kunming Institute of Botany, the Chinese Academy of Sciences, Kunming, Yunnan, China, 2001.
  3. T. G. Tutin, V. H. Heywood, N. A. Burges, D. H. Valentine, S. M. Walters, and D. A. Webb, Flora Europaea, vol. 3, Cambridge University Press, Cambridge, UK, 1972.
  4. United States Department of Agriculture, “Vitex agnus-castus L,” 2013,
  5. S. Y. Mills, Out of the Earth: The Essential Book of Herbal Medicine, Viking Arkana, London, UK, 1991.
  6. S. Y. Mills, Woman Medicine: Vitex Agnus-Castus, the Herb, Amberwood, Christchurch, UK, 1992.
  7. K. P. Odenthal, “Vitex agnus castus L.—traditional drug and actual indications,” Phytotherapy Research, vol. 12, no. 1, supplement, pp. S160–S161, 1998. View at Google Scholar
  8. A. R. Carmichael, “Can Vitex Agnus castus be used for the treatment of mastalgia? What is the current evidence?” Evidence-Based Complementary and Alternative Medicine, vol. 5, no. 3, pp. 247–250, 2008. View at Publisher · View at Google Scholar · View at Scopus
  9. G. S. Chhabra and K. S. Kulkarni, “Vitex agnus castus—an overview,” Journal of Natural Remedies, vol. 11, no. 2, pp. 90–97, 2011. View at Google Scholar
  10. S. H. Li, H. J. Zhang, S. X. Qiu et al., “Vitexlactam A, a novel labdane diterpene lactam from the fruits of Vitex agnus-castus,” Tetrahedron Letters, vol. 43, no. 29, pp. 5131–5134, 2002. View at Publisher · View at Google Scholar · View at Scopus
  11. H. Taguchi, “Studies on the constituents of Vitex cannabifolia,” Chemical and Pharmaceutical Bulletin, vol. 24, no. 7, pp. 1668–1670, 1976. View at Google Scholar · View at Scopus
  12. Y. S. Cheng and E. von Rudloff, “Two new diterpenoid oxides from the leaf oil of Chamaecyparis nootkatensis,” Tetrahedron Letters, vol. 11, no. 14, pp. 1131–1132, 1970. View at Google Scholar · View at Scopus
  13. M. Ono, Y. Ito, and T. Nohara, “Four new halimane-type diterpenes, vitetrifolins D-G, from the fruit of Vitex trifolia,” Chemical and Pharmaceutical Bulletin, vol. 49, no. 9, pp. 1220–1222, 2001. View at Publisher · View at Google Scholar · View at Scopus
  14. R. C. Bowyer and P. R. Jefferies, “Structure of spathulenol,” Chemistry & Industry, no. 30, pp. 1245–1246, 1963. View at Google Scholar
  15. A. Ulubelen, G. Topcu, C. Eris et al., “Terpenoids from Salvia sclarea,” Phytochemistry, vol. 36, no. 4, pp. 971–974, 1994. View at Publisher · View at Google Scholar · View at Scopus
  16. T. Satake, T. Murakami, Y. Saiki, and C. M. Chen, “Chemical and chemotaxonomic studies of genus Pteris and related genera (Pteridaceae)—19. Chemical studies of components of Petris-vittata L,” Chemical & Pharmaceutical Bulletin, vol. 26, no. 5, pp. 1619–1622, 1978. View at Google Scholar
  17. K. R. Markham, B. Ternai, R. Stanley, H. Geiger, and T. J. Mabry, “Carbon-13 NMR studies of flavonoids-III. Naturally occurring flavonoid glycosides and their acylated derivatives,” Tetrahedron, vol. 34, no. 9, pp. 1389–1397, 1978. View at Google Scholar · View at Scopus
  18. K. Sachdev and D. K. Kulshreshtha, “Flavonoids from Dodonaea viscosa,” Phytochemistry, vol. 22, no. 5, pp. 1253–1256, 1983. View at Google Scholar · View at Scopus
  19. E. Wollenweber and K. Mann, “Flavonols from fruits of Vitex agnus castus,” Planta Medica, vol. 48, no. 2, pp. 126–127, 1983. View at Google Scholar · View at Scopus
  20. Y. Kondo, K. Sugiyama, and S. Nozoe, “Studies on the constituents of Vitex rotundifolia L. fil,” Chemical and Pharmaceutical Bulletin, vol. 34, no. 11, pp. 4829–4832, 1986. View at Google Scholar · View at Scopus
  21. K. Gorler, D. Oehlke, and H. Soicke, “Iridoidglycoside in Vitex agnus-castus,” Planta Medica, vol. 6, pp. 530–531, 1985. View at Google Scholar · View at Scopus
  22. M. Tabata, Y. Umetani, M. Ooya, and S. Tanaka, “Glucosylation of phenolic compounds by plant cell cultures,” Phytochemistry, vol. 27, no. 3, pp. 809–813, 1988. View at Google Scholar · View at Scopus
  23. R. Li, M. A. Bianchet, P. Talalay, and L. M. Amzel, “The three-dimensional structure of NAD(P)H:quinone reductase, a flavoprotein involved in cancer chemoprotection and chemotherapy: mechanism of the two-electron reduction,” Proceedings of the National Academy of Sciences of the United States of America, vol. 92, no. 18, pp. 8846–8850, 1995. View at Google Scholar