α-Mangostin from Cratoxylum arborescens (Vahl) Blume Demonstrates Anti-Ulcerogenic Property: A Mechanistic Study
Figure 3
Histopathological evaluation. Results showed that α-mangostin (AM) at doses of 10 and 30 mg/kg ((d) and (e), resp.) and omeprazole ((c); 20 mg/kg) improved the histopathology of rats’ stomach compared to those pretreated with only Tween80 (ulcer control group, (b)). Black arrow indicates severe disruption to the epithelium surface and deep mucosa, while white arrow indicates leukocyte infiltration and edema in the submucosa layer (H and E stain; magnification: 10x).
