Analysis of Therapeutic Effect of Ilex hainanensis Merr. Extract on Nonalcoholic Fatty Liver Disease through Urine Metabolite Profiling by Ultraperformance Liquid Chromatography/Quadrupole Time of Flight Mass Spectrometry
Table 1
Effects of TTE on blood biochemical characteristics.
Parameter
4 w
6 w
Normal group
NAFLD group
Normal group
NAFLD group
EIH-treated group
Body weight (g)
279.43 ± 13.69
299.33 ± 18.94*
309.60 ± 9.79
332.60 ± 25.27△△
339.30 ± 21.74
Liver weight (g)
8.56 ± 0.53
12.78 ± 0.36**
8.318 ± 0.664
14.665 ± 1.98△△
13.165 ± 1.201#
Liver/body weight (%)
2.89 ± 0.21
4.53 ± 0.21**
2.87 ± 0.28
4.82 ± 0.20△△
3.41 ± 0.21#
TG (mg/dL)
53.53 ± 8.58
182.45 ± 57.65**
59.53 ± 9.022
85.75 ± 23.12△
52.13 ± 12.68#
TC (mg/dL)
58.46 ± 9.44
105.89 ± 12.69**
53.182 ± 4.506
92.65 ± 11.47△△
55.755 ± 8.12##
LDL-c (mg/dL)
7.430 ± 3.75
20.06 ± 11.67**
7.181 ± 2.52
25.63 ± 5.767△△
13.57 ± 7.49#
HDL-c (mg/dL)
42.71 ± 7.16
31.210 ± 7.27**
42.305 ± 11.10
21.31 ± 2.36△△
30.79 ± 6.16#
ALT (U/L)
3.57 ± 1.14
5.20 ± 2.10*
4.65 ± 0.133
7.12 ± 1.024△△
6.67 ± 0.82#
AST (U/L)
2.85 ± 1.25
6.78 ± 2.66**
3.723 ± 0.231
5.459 ± 1.026△△
3.807 ± 0.45##
FBG (mmol/L)
9.66 ± 1.25
9.07 ± 2.76
8.677 ± 0.219
10.38 ± 2.24
8.874 ± 0.93
, **, compared to normal group (4 w). △, △△, compared to normal group (6 w); #, ##, compared to NAFLD group (6 w).
