Hepatoprotective Potential of Chestnut Bee Pollen on Carbon Tetrachloride-Induced Hepatic Damages in Rats

Table 3

Histologic analysis and scoring of liver sections of the treated and untreated rats.

Groups	Hepatocyte degeneration	Vascular congestion	Sinusoidal dilatation	Congestion in enlarged sinusoids	Fatty; degeneration	Apoptosis; index (AI)
G1 (control)	0.43±0.535^a	0.57±0.535^ab	0.29±0.488^a	0.29±0.488^a	0.0±0.0^a	3.57±2.15^a
G2 (control)	0.43±0.535^a	0.71±0.488^abc	0.86±0.378^ab	0.29±0.488^a	0.0±0.0^a	4.71±1.70^a
G3 (control)	0.29±0.488^a	0.43±0.535^a	0.71±0.488^ab	0.29±0.488^a	0.0±0.0^a	3.86±1.68^a
G4 (CCI4)	2.71±0.488^c	0.71±0.488^abc	1.57±0.535^c	0.86±0.378^b	3.00±0.0^c	35.57±6.35^d
G5 (silibinin)	2.00±0.577^b	1.14±0.69^bcd	1.29±0.756^bc	0.71±0.488^ab	1.86±0.69^b	20.0±3.16^c
G6 (low pollen)	2.14±0.378^b	1.43±0.535^d	1.29±0.756^bc	0.86±0.378^b	2.14±0.69^b	21.57±4.04^c
G7 (high pollen)	1.71±0.488^b	1.29±0.488^cd	1.29±0.488^bc	0.71±0.488^ab	1.71±0.756^b	15.86±3.29^b

The histological score was calculated using a scale from 0 to 3, 0: none, 1: mild, 2: moderate, and 3: severe.
aValues are significantly different from G4, G5, G6, and G7 (𝑃<0.05).
bValues are significantly different from those of controls (G1–G3) (𝑃<0.05).
cValues are significantly different from those of silibinin (G5) (𝑃<0.05).
dValues are significantly different from G7 (400 mg pollen/kg B.W.) (𝑃<0.05).