<i>Paeonia lactiflora</i> Extract Attenuating Cerebral Ischemia and Arterial Intimal Hyperplasia Is Mediated by Paeoniflorin via Modulation of VSMC Migration and Ras/MEK/ERK Signaling Pathway

<table>Effects of PLex on PDGF-induced VSMC migration by wound healing assay. (a) A typical trace of PLex (5, 10, and 20 <i>μ</i>g/mL) inhibited in response to PDGF-induced VSMC migration. (b) Statistical differences in 24, 48, and 72 hr at different PLex concentrations, respectively. Normal group was treated with vehicle solution. *<svg height="11.375" id="M14" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> compared with PDGF control group (<svg height="11.225" id="M17" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 36.237499 11.225" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>).</table>

Evidence-Based Complementary and Alternative Medicine

fig5

Figure 5

Figure 5: <i>Paeonia lactiflora</i> Extract Attenuating Cerebral Ischemia and Arterial Intimal Hyperplasia Is Mediated by Paeoniflorin via Modulation of VSMC Migration and Ras/MEK/ERK Signaling Pathway 

Figure 5 | Paeonia lactiflora Extract Attenuating Cerebral Ischemia and Arterial Intimal Hyperplasia Is Mediated by Paeoniflorin via Modulation of VSMC Migration and Ras/MEK/ERK Signaling Pathway 