|If combined with exercise; **B in case of a comorbid depressive or generalized anxiety disorder; C in case without depressive or generalized anxiety disorder; ***In case of only one RCT with positive results, no recommendation was given. |
SNRI: serotonin noradrenaline reuptake inhibitors; SSRI: serotonin reuptake inhibitors; TCA: tricyclic antidepressant.
A: strong recommendation: the intervention should be offered to most of the patients.
B: recommendation: the intervention may be offered to the majority of patients. the intervention may not be offered to a substantial minority of the patients.
C: open recommendation: the intervention can be offered to a minority patients.