Metabonomics Combined with UPLC-MS Chemical Profile for Discovery of Antidepressant Ingredients of a Traditional Chinese Medicines Formula, Chaihu-Shu-Gan-San

<table>(a) Urinary metabolic pathways of CUMS-induced depression with CSGS or QZ treatment. Metabolites in red font: the potential biomarkers on which CSGS had regulations but QZ did not; metabolites in blue font: the potential biomarkers on which QZ had regulations but CSGS did not. (b) The levels of 12 potential biomarkers for differentiating CSGS and QZ treated. (*<svg height="11.375" id="M42" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus CUMS group).</table>

Evidence-Based Complementary and Alternative Medicine

fig3

Figure 3

Figure 3: Metabonomics Combined with UPLC-MS Chemical Profile for Discovery of Antidepressant Ingredients of a Traditional Chinese Medicines Formula, Chaihu-Shu-Gan-San 

Figure 3 | Metabonomics Combined with UPLC-MS Chemical Profile for Discovery of Antidepressant Ingredients of a Traditional Chinese Medicines Formula, Chaihu-Shu-Gan-San 