Research Article

Metabonomics Combined with UPLC-MS Chemical Profile for Discovery of Antidepressant Ingredients of a Traditional Chinese Medicines Formula, Chaihu-Shu-Gan-San

Table 2

Inhibition of synephrine, naringin, hesperidin, and neohesperidin against MAO-A activity.

No.CompoundsIC50 ( M)

iSynephrine15.23
iiNaringin5.82
iii-1Hesperidin26.72
iii-2Neohesperidin93.76
ControlMoclobemide5.25