Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 498935, 10 pages
http://dx.doi.org/10.1155/2013/498935
Research Article

Efficacy and Safety of Taeeumjowi-tang in Obese Korean Adults: A Double-Blind, Randomized, and Placebo-Controlled Pilot Trial

1Department of Preventive Medicine, College of Korean Medicine, Daejeon University, 62 Daehak-ro, Daejeon 300-716, Republic of Korea
2Department of Preventive Medicine, College of Korean Medicine, Kyung Hee University, 1 Hoegi-dong, Seoul 130-701, Republic of Korea
3Center for Clinical Research & Drug Development, Kyung Hee University, 1 Hoegi-dong, Seoul 130-701, Republic of Korea
4Family Medicine & Integrative Medicine, Seoul St. Mary’s Hospital, Catholic University Medical Center, Seoul 137-701, Republic of Korea
5Department of Internal Medicine, College of Korean Medicine, Semyung University, Bongbang-dong, Chungju 380-960, Republic of Korea
6Department of Korean Rehabilitation Medicine, College of Korean Medicine, Gachon University, Seongnam 461-701, Republic of Korea

Received 4 April 2013; Accepted 5 July 2013

Academic Editor: Chang Shik Yin

Copyright © 2013 Sunju Park et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. Ministry of Health & Welfare Korea Centers for Disease Control and Prevention, Korean National Health and Nutrition Examination Survey, Ministry of Health & Welfare Korea Centers for Disease Control and Prevention, Seoul, Republic of Korea, 2011.
  2. S. M. Park, I. S. Ahn, D. S. Kim, S. Kang, D. Y. Kwon, and H. J. Yang, “Anti-obesity effects of Tae-Um-Jo-Wee-Tang and Do-Dam-Tang in female rats with diet-induced obesity,” Journal of Applied Biological Chemistry, vol. 53, no. 1, pp. 44–50, 2010. View at Publisher · View at Google Scholar · View at Scopus
  3. B. G. Jeong, O. R. Moon, N. S. Kim et al., “Socioeconomic costs of obesity for Korean adults,” Journal of Preventive Medicine and Public Health, vol. 35, no. 1, pp. 1–12, 2002. View at Google Scholar
  4. J. G. Kang and C. Y. Park, “Anti-obesity drugs: a review about their effects and safety,” Journal of Diabetes & Metabolism, vol. 36, no. 1, pp. 13–25, 2012. View at Google Scholar
  5. W. P. James, I. D. Caterson, W. Coutinho et al., “Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects,” The New England Journal of Medicine, vol. 363, no. 10, pp. 905–917, 2010. View at Google Scholar
  6. WHO, “Obesity: preventing and managing the global epidemic,” Report of a WHO Consultation 0512-3054, WHO, Geneva, Switzerland, 2000. View at Google Scholar
  7. K. S. Kim, D. U. Lee, Y. L. Kim et al., “Anti-obesity and anti-hyperlipidemic effects of Taeyeumjowee-tang and its modified prescription,” Journal of Oriental Neuropsychiatry, vol. 18, no. 2, pp. 57–74, 2007. View at Google Scholar
  8. WHO International Standard Terminologies on Traditional Medicine in the Western Pacific Region, WHO International Standard Terminologies on Traditional Medicine in the Western Pacific Region, WHO, Geneva, Switzerland, 2007.
  9. S. Park, J. S. Park, C. Cheon et al., “A pilot study to evaluate the effect of Taeumjowi-tang on obesity in Korean adults: study protocol for a randomised, double-blind, placebo-controlled, multicentre trial,” Trials, vol. 13, p. 33, 2012. View at Google Scholar
  10. A. V. Chobanian, G. L. Bakris, H. R. Black et al., “The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report,” Journal of the American Medical Association, vol. 289, no. 19, pp. 2560–2572, 2003. View at Publisher · View at Google Scholar · View at Scopus
  11. C. Y. Park, Y. S. Kim, M. S. Ryu et al., “A phase 3 double-blind, parallel-group, placebo-controlled trial of the efficacy and safety of sibutramine (Reductil) in the treatment of obese patients,” The Korean Journal of Obesity, vol. 10, no. 4, pp. 336–347, 2001. View at Google Scholar
  12. C. N. Boozer, P. A. Daly, P. Homel et al., “Herbal ephedra/caffeine for weight loss: a 6-month randomized safety and efficacy trial,” International Journal of Obesity, vol. 26, no. 5, pp. 593–604, 2002. View at Publisher · View at Google Scholar · View at Scopus
  13. F. L. Greenway, “The safety and efficacy of pharmaceutical and herbal caffeine and ephedrine use as a weight loss agent,” Obesity Reviews, vol. 2, no. 3, pp. 199–211, 2001. View at Google Scholar · View at Scopus
  14. R. M. Hackman, P. J. Havel, H. J. Schwartz et al., “Multinutrient supplement containing ephedra and caffeine causes weight loss and improves metabolic risk factors in obese women: a randomized controlled trial,” International Journal of Obesity, vol. 30, no. 10, pp. 1545–1556, 2006. View at Publisher · View at Google Scholar · View at Scopus
  15. S. Hasani-Ranjbar, N. Nayebi, B. Larijani, and M. Abdollahi, “A systematic review of the efficacy and safety of herbal medicines used in the treatment of obesity,” World Journal of Gastroenterology, vol. 15, no. 25, pp. 3073–3085, 2009. View at Publisher · View at Google Scholar · View at Scopus
  16. G. B. Lenon, K. X. Li, Y. H. Chang et al., “Efficacy and safety of a Chinese herbal medicine formula (RCM-104) in the management of simple obesity: a randomized, Placebo-controlled clinical trial,” Evidence-Based Complementary and Alternative Medicine, vol. 2012, Article ID 435702, 11 pages, 2012. View at Publisher · View at Google Scholar
  17. National Heart, Lung, and Blood Institute, Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults, National Heart, Lung, and Blood Institute, Bethesda, Md, USA, 1998.
  18. M. Sakurai, K. Miura, T. Takamura et al., “Gender differences in the association between anthropometric indices of obesity and blood presssure in Japanese,” Hypertension Research, vol. 29, no. 2, pp. 75–80, 2006. View at Publisher · View at Google Scholar · View at Scopus