Evidence-Based Complementary and Alternative Medicine / 2013 / Article / Fig 2

Research Article

6-Shogaol Protects against Oxidized LDL-Induced Endothelial Injruries by Inhibiting Oxidized LDL-Evoked LOX-1 Signaling

Figure 2

Effects of 6-shogaol against oxidized low-density lipoprotein- (oxLDL-) induced cell injuries. Human umbilical vein endothelial cells (HUVECs) were exposed to 200 μg/mL oxLDL and 1, 5, 10, and 30 μM 6-shogaol, and a combination of 6-shogaol and oxLDL. (a) Effects of 6-shogaol on SOD activities in endothelial cells in response to oxLDL; (b) cell viability was assayed using a trypan blue exclusion method.(c) Cell apoptosis was determined using flow cytometry. Each value represents the mean ± s.e.m. for . The symbols * and #, respectively, indicate that values significantly differ from the control and oxLDL-treated groups, .

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