Hu-Lu-Ba-Wan Attenuates Diabetic Nephropathy in Type 2 Diabetic Rats through PKC-α/NADPH Oxidase Signaling Pathway

Table 4

The effect of HLBW on renal function and proteinuria of rats with DN.

Group	Kidney/body weight (%)	BUN (mmol/L)	SCr (μmol/L)	Urinary total protein (𝜇g/24 h)	Urinary albumin (𝜇g/24 h)
Control	0.42±0.04	3.96±0.81	146.86±12.39	6.71±2.39	0.08±0.03
Diabetic	0.64±0.12^△△	11.46±1.50^△△	229.61±30.10^△△	50.79±7.41^△△	3.54±1.19^△△
TFG	0.48±0.08^▴▴	5.68±1.53^▴▴	184.89±15.72^▴▴	13.40±5.22^▴▴	0.41±0.35^▴▴
PC	0.43±0.06^▴▴	5.70±1.02^▴▴	183.34±23.61^▴▴	17.30±8.30^▴▴	0.54±0.37^▴▴
HLBW	0.42±0.04^▴▴	4.88±0.93^▴▴	165.16±16.56^▴▴	10.74±6.62^▴▴	0.31±0.21^▴▴
Captopril	0.45±0.06^▴▴	6.69±1.78^▴▴	190.13±21.62^▴▴	14.00±4.08^▴▴	0.40±0.28^▴▴

Values are mean ± SD (𝑛=8). ^△△𝑃<0.01 versus the control group, ^▴▴𝑃<0.01 versus the untreated diabetic group. BUN: blood urea nitrogen; SCr: serum creatinine.