A Systems Biology Approach to Characterize Biomarkers for Blood Stasis Syndrome of Unstable Angina Patients by Integrating MicroRNA and Messenger RNA Expression Profiling
Table 5
Clinical characteristics of subjects of qRT-PCR.
UA with BSS ()
UA with non-BSS ()
Controls ()
value
Male gender ()
15 (50%)
15 (50%)
8 (53.3%)
0.974
Age (years)
0.896
BMI (kg/m2)
0.231
Active smoker ()
17 (56.7%)
18 (60%)
6 (40%)
0.429
BSS Grades
0
Number of vessels ()
0
Hypertension ()
22 (73.3%)
23 (76.7%)
0
0.000
Type 2 diabetes mellitus ()
14 (46.7%)
15 (50%)
0
0.001
Total cholesterol (mmol/L)
0.172
LDL cholesterol (mmol/L)
0.436
HDL cholesterol (mmol/L)
0.032
Triglycerides (mmol/L)
0.001
CRP (mg/L)
0.122
Concurrent medication ()
Antiplatelet
100%
28 (93.3%)
0
0.000
Beta-blocker
20 (66.7%)
20 (66.7%)
0
0.000
ACEI/ARB
18 (60%)
16 (53.3%)
0
0.000
Calcium-channel blockers
13 (43.3%)
15 (50%)
0
0.001
Nitrates
22 (73.3%)
20 (66.7%)
0
0.000
Statin
26 (86.7%)
24 (80%)
0
0.000
Data represents means ± SEM. Abbreviations: ACEI: angiotensin-converting enzyme inhibitor; ARB: angiotensin receptor blocker; BMI: body mass index; BSS: blood stasis syndrome; HDL: high-density protein; CRP: C-reactive protein; LDL: low-density protein.