Gastrodin Protects Apoptotic Dopaminergic Neurons in a Toxin-Induced Parkinson’s Disease Model
Figure 1
Effect of gastrodin on MPP+-induced neurotoxicity in the dopaminergic neuroblastoma SH-SY5Y cell line. Cells were exposed to gastrodin and 1 mM MPP+ for 48 h. Cell viability (A) and morphology of SH-SY5Y cells (B) after treatment with control (a), 1 mM MPP+ (b), 25 μM gastrodin (c), 25 μM gastrodin + 1 mM MPP+ (d), 5 μM gastrodin + 1 mM MPP+ (e), and 1 μM gastrodin + 1 mM MPP+ (f). Data are percentages of values in the untreated control cultures and are means ± standard errors of three independent experiments in triplicate. compared with the control group, , and compared with the MPP+-treated group (one-way analysis of variance followed by Tukey’s post hoc test).