The effect of PN-1, a Traditional Chinese Prescription, on the Learning and Memory in a Transgenic Mouse Model of Alzheimer’s Disease

Figure 2

Effects of PN-1 treatment (mg/kg once a day) on the performance of the Morris water maze test. (a) The escape latency time in 5 days in the hidden platform test. Each point represents the mean latency of two trials per day for 5 consecutive days of testing. (b) The frequency of crossing within the platform quadrant detected in the probe trial. (c) An illustration of typical behavioral traces in the probe trial. Data represent means ± SEM (𝑛=17 mice/group). ^∗𝑃<0.05, ^∗∗𝑃<0.01 versus the vehicle-treated group; ^##𝑃<0.01 versus the wild-type group.

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