Multicomponent Therapeutics of Berberine Alkaloids

Figure 5

The excess over the highest single agent model, including 10 combinations of the 5 berberine alkaloids. Purple squares indicate strong antagonistic effect, orange squares indicate slight antagonistic effect, dark blue squares indicate additive effect, light blue squares indicate slight synergistic effect, brilliant yellow squares indicate strong slight synergistic effect, and green squares indicate strong synergistic effect.