Evidence-Based Complementary and Alternative Medicine / 2013 / Article / Tab 1

Research Article

In Vitro Evaluations of Cytotoxicity of Eight Antidiabetic Medicinal Plants and Their Effect on GLUT4 Translocation

Table 1

GLUT4 translocation and EC50 of plant extracts in cells from HepG2 and L6myc cell lines. Data given represent the mean ± SEM from three independent experiments carried out in triplicates.

Plant namePart usedCell typeEC50 (mg/mL)Cell surface* GLUT4myc

Allium sativum BulbL6myc>2
HepG2>2
Allium cepa BulbL6myc>2
HepG2>2
Trigonella foenum SeedsL6myc>2++
HepG2>2
Olea europaea LeavesL6myc0.79 ± 0.036− −
HepG2>2
Nigella sativa SeedsL6myc>2+
HepG21.47 ± 0.49
Urtica dioica Leaves and stemL6myc0.73 ± 0.09++
HepG20.76 ± 0.13
Atriplex halimus Leaves and stemL6myc1.72 ± 0.22++
HepG20.8 ± 0.3
Cinnamomon cassia BarkL6myc0.39 ± 0. 01+
HepG20.12 ± 0. 01

*Gain in GLUT4 on plasma membranes at noncytotoxic concentrations, (−) no effect, (− −) decreased GLUT4 translocation, (+) slightly increased the GLUT4 translocation, (++) high GLUT4 translocation.