Anacardic Acids from Cashew Nuts Ameliorate Lung Damage Induced by Exposure to Diesel Exhaust Particles in Mice
Figure 7
8-isoprostane (a), KC (b), TNF- (c) and NF-B (d) in the alveolar parenchyma. Values represent means ± SEM or medians (interquartile range). Ctrl: control; animals received an intranasal instillation of 10 L saline solution and were treated orally with 100 L of cashew nut oil (CNO). DEP: intranasal instillation of 50 g DEP/10 L of saline and treated orally with 100 L of CNO. DA50: intranasal instillation of 50 g DEP/10 L of saline and treated orally with 50 mg/kg of AAs. DA150: intranasal instillation of 50 g DEP/10 L of saline and treated orally with 150 mg/kg of AAs. DA250: intranasal instillation of 50 g DEP/10 L of saline and treated orally with 250 mg/kg of AAs. KC: keratinocyte chemoattractant. TNF-: tumor necrosis factor-alpha. NF-B: nuclear factor-kappa B. relative to Ctrl. relative to DEP.
