Research Article

Gene Expression Profile of the A549 Human Non-Small Cell Lung Carcinoma Cell Line following Treatment with the Seeds of Descurainia sophia, a Potential Anticancer Drug

Table 1

IC50 of EEDS in human lung cancer cell lines.

Cell linesNCI60 panelDiseaseDrug expose (h)IC50
EEDS (μg/mL)Dox (μM)a

A549YesLung cancer243.72 ± 1.12n.d.
482.81 ± 0.190.04 ± 0.00
722.15 ± 0.01n.d.
962.59 ± 0.16n.d.
NCI-H23YesLung cancer486.60 ± 0.180.22 ± 0.04
NCI-H226YesLung cancer4813.18 ± 0.770.33 ± 0.04
NCI-H460YesLung cancer488.08 ± 0.010.31 ± 0.04
IMR-90Normal lung4810.54 ± 0.790.40 ± 0.04

Dox, doxorubicin, was included as a reference anticancer drug [12].