Gene Expression Profile of the A549 Human Non-Small Cell Lung Carcinoma Cell Line following Treatment with the Seeds of Descurainia sophia, a Potential Anticancer Drug
Table 1
IC50 of EEDS in human lung cancer cell lines.
Cell lines
NCI60 panel
Disease
Drug expose (h)
IC50
EEDS (μg/mL)
Dox (μM)a
A549
Yes
Lung cancer
24
3.72 ± 1.12
n.d.
48
2.81 ± 0.19
0.04 ± 0.00
72
2.15 ± 0.01
n.d.
96
2.59 ± 0.16
n.d.
NCI-H23
Yes
Lung cancer
48
6.60 ± 0.18
0.22 ± 0.04
NCI-H226
Yes
Lung cancer
48
13.18 ± 0.77
0.33 ± 0.04
NCI-H460
Yes
Lung cancer
48
8.08 ± 0.01
0.31 ± 0.04
IMR-90
—
Normal lung
48
10.54 ± 0.79
0.40 ± 0.04
Dox, doxorubicin, was included as a reference anticancer drug [12].