Gene Expression Profile of the A549 Human Non-Small Cell Lung Carcinoma Cell Line following Treatment with the Seeds of Descurainia sophia, a Potential Anticancer Drug
Table 4
Top 10 GO terms associated with Up- and Down-patterns by EEDS treatment.
GO ID
GO terms
value*
FDR**
Down-pattern
GO:0051188
Cofactor biosynthetic process
GO:0051186
Cofactor metabolic process
GO:0018130
Heterocycle biosynthetic process
GO:0044271
Nitrogen compound biosynthetic process
GO:0006399
tRNA metabolic process
Up-pattern
GO:0045449
Regulation of transcription
GO:0006350
Transcription
GO:0006355
Regulation of transcription, DNA-dependent
GO:0051252
Regulation of RNA metabolic process
GO:0006357
Regulation of transcription from RNA polymerase II promoter
GO:0042325
Regulation of phosphorylation
GO:0051173
Positive regulation of nitrogen compound metabolic process
GO:0045859
Regulation of protein kinase activity
GO:0019220
Regulation of phosphate metabolic process
GO:0051174
Regulation of phosphorus metabolic process
values were calculated using Fischer’s test. FDR corrections were calculated using the Benjamini-Hochberg procedure in DAVID program [17].