Inhibition of LXR𝜶/SREBP-1c-Mediated Hepatic Steatosis by Jiang-Zhi Granule

Figure 2

JZG reduced HFD-induced expression of lipogenesis-related genes and proteins. (a) The effect of JZG on HFD-induced LXR𝛼, SREBP-1c, and FAS mRNA expression levels. (b) The effect of JZG on HFD-induced LXR𝛼, pSREBP-1, mSREBP-1, and FAS protein expression levels. Data were presented as the mean ± SEM. *𝑃<0.05 and **𝑃<0.01 versus the control group, ^#𝑃<0.05 and ^##𝑃<0.01 versus the HFD group.

(a)

(b)