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Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 587234, 16 pages
Research Article

Investigation into the Influence of Physician for Treatment Based on Syndrome Differentiation

1Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, No. 16 NanXiaoJie, DongZhiMenNei, Dong Cheng District, Beijing 100700, China
2China Academy of Chinese Medical Sciences, No. 16 NanXiaoJie, DongZhiMenNei, Dong Cheng District, Beijing 100700, China
3Community Health Management Center of Dong Cheng District, No. 2 He Ping Li Dong Jie & Jiao Lin Jia Dao Jia, Dong Cheng District, Beijing 100013, China
4Guang’anmen Hospital, China Academy of Chinese Medical Sciences, No. 5 BeiXianGe, GuangAnMenNei, XiCheng District, Beijing 100053, China
5School of Computer and Information Technology, Beijing Jiaotong University, No. 3 Shangyuancun, HaiDian District, Beijing 100044, China

Received 4 April 2013; Revised 2 August 2013; Accepted 14 August 2013

Academic Editor: Vincent Chi-Ho Chung

Copyright © 2013 Lijie Jiang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. The characteristics of treatment based on syndrome differentiation (TBSD) cause great challenges to evaluate the effectiveness of the clinical methods. Objectives. This paper aims to evaluate the influence of physician to personalized medicine in the process of TBSD. Methods. We performed a randomized, triple-blind trial involving patients of primary insomnia treated by 3 physicians individually and independently. The patients ( ) were randomly assigned to receive treatments by the 3 physicians for every visit. However, they always received the treatment, respectively, prescribed by the physician at the first visit. The primary outcome was evaluated, respectively, by the Pittsburgh Sleep Quality Index (PSQI) and the TCM symptoms measuring scale. The clinical practices of the physicians were recorded at every visit including diagnostic information, syndrome differentiation, treating principles, and prescriptions. Results. All patients in the 3 groups (30 patients) showed significant improvements (>66%) according to the PSQI and TCM symptoms measuring scale. Conclusion. The results indicate that although with comparable effectiveness, there exist significant differences in syndrome differentiation, the treating principles, and the prescriptions of the approaches used by the 3 physicians. This means that the physician should be considered as an important factor for individualized medicine and the related TCM clinical research.