The Protective Effect of Alpha-Lipoic Acid in Lipopolysaccharide-Induced Acute Lung Injury Is Mediated by Heme Oxygenase-1

Figure 6

Effect of SnPP on the inhibition of ALA on LPS-induced proinflammatory cytokine and CINC-3 production in BALF. Rats were pretreated with ALA 1 h before intratracheal instillation of LPS for 6 h. In some rats, SnPP was administered 2 h and ALA 1 h before LPS instillation. Data were presented as means ± SEM (𝑛=5). *𝑃<0.05; **𝑃<0.01 versus LPS-instilled alone group; ^#𝑃<0.05 versus LPS+ALA group.

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