The Protective Effect of Alpha-Lipoic Acid in Lipopolysaccharide-Induced Acute Lung Injury Is Mediated by Heme Oxygenase-1
Figure 9
Effect of SnPP on the reduction of ALA on LPS-induced NF-κB activation in lungs. Rats were pretreated with ALA 1 h before intratracheal instillation of LPS for 6 h. In some rats, SnPP was administered 2 h and ALA 1 h before LPS instillation. The expression of phospho-NFκB-p65 in nucleus of lungs with immunofluorescence stains was determined (a) and semiquantified (b) at 6 h after LPS instillation. Data were represented as means ± SEM (). * versus LPS-instilled alone group.
