Review Article
The Anti-Inflammatory Effects of Acupuncture and Their Relevance to Allergic Rhinitis: A Narrative Review and Proposed Model
| Role of NGF in allergic rhinitis: | (i) increases neuronal abundance in nasal epithelium leading to hypersensitivity and increased tendency to nasal congestion | (ii) increases expression and sensitivity of TRPV1 receptors in nasal epithelium | (iii) prolongs survival of eosinophils and mast cells (prolonging inflammatory response) | (iv) contributes to early-phase allergic response (but not to late-phase response) | (v) increases production and release of pro-inflammatory neuropeptides SP and CGRP |
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