Evidence-Based Complementary and Alternative Medicine

Research Article

A Network-Based Systematic Study for the Mechanism of the Treatment of Zhengs Related to Cough Variant Asthma

Table 4

Module functions.


Module	Aspect	Enriched items

1	GO process	Response to organic substance Lipid metabolic process Regulation of biological quality Hormone biosynthetic process Androgen metabolic process
	GO Molecular functions	Oxidoreductase activity Acting on the CH-CH group of donors Steroid dehydrogenase activity NAD or NADP as acceptor Catalytic activity
	GO localizations	Cell fraction Insoluble fraction Membrane fraction Cytoplasmic part Cell body fiber
	Pathways	Androstenedione and testosterone biosynthesis and metabolism Immune response_Gastrin in inflammatory response

2	GO process	Developmental process Regulation of cell death Response to organic substance Positive regulation of developmental process Response to stress
	GO molecular functions	Regulatory region nucleic acid binding Transcription factor binding Protein binding Regulatory region DNA binding
	GO localizations	Insoluble fraction Cell projection Dendrite Neuron projection
	Pathways	EGFR signaling pathways IL-17 signaling pathways Immune response_C5a signaling Immune response_IL-3 activation and signaling pathway Immune response_IL-5 signalling Immune response_IL-6 signaling pathway Apoptosis and survival_Role of CDK5 in neuronal death and survival Development_VEGF signaling via VEGFR2-generic cascades Mucin expression in CF via IL-6 Mucin expression in CF via TLRs

3	GO process	Aminoglycoside antibiotic metabolic process Synaptic transmission Gamma-aminobutyric acid signaling Inorganic anion transport Multicellular organismal process
	GO molecular functions	Alcohol dehydrogenase (NADP+) activity Ligand-gated channel activity Benzodiazepine receptor activity GABA receptor activity Chloride transmembrane transporter activity Passive transmembrane transporter activity
	GO localizations	Ion channel complex Chloride channel complex Neuronal cell body membrane Cell body membrane Synaptic membrane
	Pathways	Triacylglycerol metabolism p.1 Immune response_MIF-mediated glucocorticoid regulation