Inhibitory Effects of Standardized Extracts of Phyllanthus amarus and Phyllanthus urinaria and Their Marker Compounds on Phagocytic Activity of Human Neutrophils

Table 3

IC₅₀ values (μg/mL) of ROS inhibitory and chemotaxis activities of Phyllanthus sp. and their chemical markers on phagocytes (Mean ± SEM, 𝑛=3). IC₅₀ values in μM are in parentheses.

Sample	Chemotaxis	Chemiluminescence
		Whole blood	PMNs
Phyllanthus amarus  (Ind)	5.1±0.4	5.2±1.1	1.9±0.1
Phyllanthus urinaria  (Ind)	5.4±0.7	11.9±0.9	1.9±0.1
Phyllanthus amarus  (Mal)	1.1±0.1	1.1±0.9	0.7±0.2
Phyllanthus urinaria  (Mal)	1.4±0.2	1.6±0.5	0.7±0.3
Phyllanthin	3.2±0.1	3.7±2.8	3.2±0.8
	(7.6±0.1 μM)	(8.8±1.0 μM)	(7.6±0.4 μM)
Hypophyllanthin	4.4±0.2	3.6±1.4	6.1±2.3
	(10.2±0.4 μM)	(8.4±1.3 μM)	(14.2±1.7 μM)
Ibuprofen	1.4±0.1
	(6.8±0.1 μM)
Aspirin		2.2±0.8	1.9±0.2
		(12.2±1.1 μM)	(10.5±2.1 μM)