Amelioration of Cadmium-Produced Teratogenicity and Genotoxicity in Mice Given Arthrospira maxima (Spirulina) Treatment

Table 2

Effects of treatment with cadmium (Cd) and Arthrospira maxima (AM) on pregnancy and reproductive outcome in mice.

Treatment; (mg/kg)	Maternal weight gain (g)	Implantations; per mother	Resorptions; per litter	Live fetuses	Fetal crown-rump length (cm)	Fetal weight; (g)	Placental diameter (cm)	Placental weight (mg)
Water	28.12±1.29	13.11±0.5	0.53±0.13	96	2.09±0.07	1.21±0.42	0.81±0.03	0.10±0.01
Tween	29.11±1.30	13.21±0.7	1.02±0.67	95	2.14±0.08	1.23±0.20	0.80±0.03	0.10±0.02
AM (800)	29.62±1.12	12.67±0.5	0.97±0.14	94	2.12±0.11	1.16±0.31	0.81±0.02	0.10±0.01
Cd (1.5)	25.12±1.93	13.33±0.4	1.86±1.23	92	1.90±0.06^a	0.97±0.22^a	0.79±0.07	0.09±0.02
AM + Cd (200)	27.32±1.52	13.03±0.9	1.79±0.78	98	1.98±0.02^a	1.01±0.36^a	0.80±0.01	0.10±0.01
AM + Cd (400)	27.45±1.35	12.72±0.6	1.54±0.84	93	1.97±0.01^a	1.11±0.31^a	0.81±0.02	0.09±0.01
AM + Cd (800)	30.04±0.78	12.65±0.3	1.40±0.77	90	2.02±0.02	1.13±0.41	0.78±0.03	0.10±0.03

The determinations were made with 8 pregnant mice per group. Results are shown as the mean ± SEM. Values inside parenthesis represent percentage. ^aStatistically significant difference with respect tothe control value and ^bwith respecttothe value of Cd treated mice. One-way ANOVA and Student Newman Keuls tests; 𝑃<0.05.