Protective Mechanisms of S. lycopersicum Aqueous Fraction (Nucleosides and Flavonoids) on Platelet Activation and Thrombus Formation: In Vitro, Ex Vivo and In Vivo Studies
Figure 2
Effects of total extract on platelet aggregation. (a) PRP was incubated with saline or total extract (1 mg/mL) as indicated for 3 min, prior to measuring human platelet aggregation induced by ADP 8 µM, collagen 1.5 μg/mL, AA (arachidonic acid 1 mM) or TRAP-6 30 µM, and (b) PRP was incubated with saline or total extract (1 mg/mL) for 20, 60, and 180 seconds, prior to measuring human platelet aggregation induced by ADP 8 µM. The graph depicts the mean ± SEM of experiments. *. PRP: platelet-rich plasma.
