Evidence-Based Complementary and Alternative Medicine / 2013 / Article / Tab 1

Research Article

Interaction of Natural Dietary and Herbal Anionic Compounds and Flavonoids with Human Organic Anion Transporters 1 (SLC22A6), 3 (SLC22A8), and 4 (SLC22A11)

Table 1

Maximum plasma concentration ( ) reported in human subjects.

Compound ( M)Route of administrationDose (mg)Reference

Epicatechin0.20Oral37[7]
1,5-Dicaffeoylquinic acid0.14Oral600[23]
18β-Glycyrrhetinic acid0.11–2.9aOral130–144 (glycyrrhizin)[12, 24, 25]
Ursolic acid7.4i.v.186[13]

Assuming plasma concentration of 18α- and 18β-glycyrrhetinic acid is about 1 : 3 as reported in [12].

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