Research Article

Antimicrobial Activity of Lippia Species from the Brazilian Semiarid Region Traditionally Used as Antiseptic and Anti-Infective Agents

Table 2

Minimum inhibitory concentration (MIC) of the crude extract and fractions from L. origanoides and reference antibiotics.

SamplesMinimum inhibitory concentration (mg mL−1)
E. coli
CCMB261
S. aureus
CCMB262
S. aureus
CCMB263
P. aeruginosa
CCMB268
C. albicans
CCMB286
C. parapsilosis
CCMB288

L. origanoides leaves
CEXL5.2631.3160.6585.2632.6312.631
HEFL1.3160.3292.631
DIFL0.6582.6311.316
EAFL0.6580.3292.631
AQFL2.6312.6312.631

L. origanoides stems
CEXS5.2635.2632.6315.2632.6315.263
HEFS2.6310.6582.631
DIFS0.6582.6310.658
EAFS1.3162.6312.631
AQFS5.2635.2632.631

Chloramphenicol10 0.078 0.313 5

Nystatin1.252.5

(—): not evaluated; CEX: crude extract; HEF: hexane fraction; DIF: dichloromethane fraction; EAF: ethyl acetate fraction; AQF: aqueous fraction; L: leaves; S: stems. MIC = 2.631 mg mL−1 was the maximum value considered for attribution of antimicrobial activity for each strain.