Involvement of Endoplasmic Reticulum Stress in Capsaicin-Induced Apoptosis of Human Pancreatic Cancer Cells
Figure 6
Effect of capsaicin on the tumor metabolisms, weights, and volumes in pancreatic cancer xenograft tumor mice (control, PBS; CAP 1, capsaicin, 1 mg/kg; CAP 2.5, capsaicin, 2.5 mg/kg; CAP 5, capsaicin, 5 mg/kg). (a) Micro-PET imaging. Micro-PET imaging was performed one week after the last treatment. The values of SUV are expressed as mean ± SD and analyzed by one-way ANOVA followed by Dunnett’s test, and compared with the control group. (b) Tumor weights. One week after the last treatment, the mice were sacrificed and tumors were removed. The tumors were weighted with an electronic balance. Data are expressed as mean ± SD and analyzed by one-way ANOVA followed by Dunnett’s test, and compared with the control group. (c) Tumor volumes. Tumor volumes were calculated with a vernier caliper with the following formula: . Data are expressed as mean ± SD and analyzed by one-way ANOVA followed by Dunnett’s test, and compared with the control group.
