Systemic Revealing Pharmacological Signalling Pathway Networks in the Hippocampus of Ischaemia-Reperfusion Mice Treated with Baicalin

Figure 5

Subnetworks 1, 2, and 4 of 9 networks in baicalin group. The subnetwork 1 primarily consisted of Shc, c-src, VEGF-A, paxillin, and SMAD3, and its major function was regulation of cellular metabolic process. The centre of subnetwork 2 is p21 whose major function was positive regulation of nitrogen compound metabolic process and positive regulation of cellular biosynthetic process. The centre of subnetwork 4 is cyclin D whose major function was positive regulation of macromolecule metabolic process.