Magnolol Ameliorates Ligature-Induced Periodontitis in Rats and Osteoclastogenesis: In Vivo and In Vitro Study

Figure 4

Effect of magnolol on MPO activity, superoxide anion production, and expression of COX-2 and iNOS in inflamed periodontal tissues. (a) The MPO activity and (b) superoxide anion production were determined in the gingivomucosal tissues of each experimental group. (c) The Western blot analysis was used to detect COX-2 and iNOS protein level in dissected tissues encircled upper second molar. Data are expressed as the mean ± SD (𝑛=5). ***𝑃<0.001 versus control; ^#𝑃<0.05, ^##𝑃<0.01, and ^###𝑃<0.001 versus ligation group.

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