Magnolol Ameliorates Ligature-Induced Periodontitis in Rats and Osteoclastogenesis: In Vivo and In Vitro Study

Figure 5

Effect of magnolol on MMP-1, -9, and TIMP-1 expression and NF-κB activation. (a) The protein expression of MMP-1, -9, and TIMP-1 was determined by Western blot in dissected tissues encircled upper second molar, and the relative MMPs/TIMP ratio was measured. (b) The Western blot analysis was conducted to detect phospho-NF-κB p65 protein level in dissected tissues. Data are expressed as the mean ± SD (𝑛=4). **𝑃<0.01, ***𝑃<0.001 versus control; ^#𝑃<0.05, ^##𝑃<0.01 versus ligation group.

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