A Single-Center, Randomized Double-Blind Placebo-Controlled Study Evaluating the Effects of Poly-Gamma-Glutamate on Human NK Cell Activity after an 8-Week Oral Administration in Healthy Volunteers
Figure 2
Lytic activity of PBMCs in the intention-to-treat (ITT) group. PBMCs were isolated from the test subjects who were treated with the low dosage of γ-PGA, high-dosage of γ-PGA, or no γ-PGA, and they were incubated with K562 cells for 5 h at an effector cell (PBMC) to target cell (K562) ratio of 30 : 1. Cytotoxicity was determined by the analysis of LDH release. values are given compared to the baseline for the high-dosage, low dosage, and placebo groups. The results are given as the mean ± SD for donors; .
