A Single-Center, Randomized Double-Blind Placebo-Controlled Study Evaluating the Effects of Poly-Gamma-Glutamate on Human NK Cell Activity after an 8-Week Oral Administration in Healthy Volunteers

<table>PBMCs from healthy donors were incubated with or without <i>γ</i>-PGA for 8 hours and then stimulated with K562 cells for an additional 7 hours. (a) Dot plots show CD56<sup>+</sup>CD3<sup>−</sup> NK cells stained for CD107a from a representative donor. Inset numbers indicate the percentage of NK cells that displayed CD107a. (b) Bar graph shows the average percentage of CD107a<sup>+</sup> NK cells from 13 donors; <svg height="13.95" id="M38" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 96.612503 13.95" width="96.612503" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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Evidence-Based Complementary and Alternative Medicine

fig4

Figure 4

Figure 4: A Single-Center, Randomized Double-Blind Placebo-Controlled Study Evaluating the Effects of Poly-Gamma-Glutamate on Human NK Cell Activity after an 8-Week Oral Administration in Healthy Volunteers 

Figure 4 | A Single-Center, Randomized Double-Blind Placebo-Controlled Study Evaluating the Effects of Poly-Gamma-Glutamate on Human NK Cell Activity after an 8-Week Oral Administration in Healthy Volunteers 