Table 1: Diabetic animal models employed in studying the effect of curcumin on glycemia.

AnimalInduction of diabetes
(route and dose)
Curcumin
(route and dose)
Course of
treatment
Reference

Wistar ratsi.f. of STZ, 55 mg/kg·BWOral, 60 mg/kg·BW14 days[17, 18]
Wistar ratsi.p. of STZ, 55 mg/kg·BW; HFDOral, 150 mg/kg·BW42 days[19]
SD ratsHFDOral, 80 mg/kg·BW15 and 60 days [26]
SD ratsi.p. of STZ, 55 mg/kg·BW Oral, 100 mg/kg·BW28 days; 56 days[21, 23]
Wistar ratsInjection of STZ, 45 mg/kg·BW0.5% curcumin in diet16 weeks[27]
Wistar ratsi.p. of STZ, 55 mg/kg·BWOral, 300 mg/kg·BW56 days[20]
Wistar ratsi.p. of alloxan monohydrate
(150 mg/kg·BW)
Oral, 80 mg/kg·BW21 days[15]
Swiss micei.p. of STZ
(40 mg/kg·BW)
i.p., 10 mM28 days[32]
C57BL/6J mice HFDOral, 50 mg/kg·BW15 days[33]
C57BL/6J mice: ob/ob miceHFD0.5% curcumin in diet42 days[29]
db/db miceNot Applicable0.02% curcumin in diet42 days[30]

i.f.: intrafemoral injection, i.p.: intraperitoneally injection.