Coniferyl Ferulate, a Strong Inhibitor of Glutathione S-Transferase Isolated from Radix Angelicae sinensis, Reverses Multidrug Resistance and Downregulates P-Glycoprotein
Figure 4
(a) A Hanes plot of versus [S] for GSH. The reaction was carried out at 37°C for 5 min after preincubating GST with CF for 5 min. A Hanes plot of versus [S] was created for GSH concentrations from 0.07 to 2.24 mM. (b) A Hanes plot of versus [S] was created for CDNB concentrations from 0.5 to 44.1 μM. The CF concentrations were 0 μM, 0.25 μM, and 0.5 μM.
