Coniferyl Ferulate, a Strong Inhibitor of Glutathione S-Transferase Isolated from Radix Angelicae sinensis, Reverses Multidrug Resistance and Downregulates P-Glycoprotein
Figure 7
Effect of CF on MDR1 expression in B-MD-C1 (ADR+/+) cells. Cells were incubated with various concentrations of CF (5 μM, 10 μM, and 20 μM) or Adriamycin (5 μg/mL) for 48 h. EA (40 μM) as positive control. MDR1 bands were noted in (a). Densitometric analysis is shown in (b). # B-MD-C1 versus B-MD-C1 (ADR+/+), * compound (+)/Adriamycin (+) versus compound (−)/Adriamycin (+) group. All the data shown are representative of three independent experiments.
