Research Article

Coniferyl Ferulate, a Strong Inhibitor of Glutathione S-Transferase Isolated from Radix Angelicae sinensis, Reverses Multidrug Resistance and Downregulates P-Glycoprotein

Table 2

Flow cytometry data for the effect of CF on apoptosis of B-MD-C1 (ADR+/+) cells ( , ).

Treatment G1%S%Apoptosis (%)

Control57.30 ± 7.2641.87 ± 7.394.82 ± 1.38
EA, 40  M76.63 ± 4.23*6.07 ± 3.86*16.83 ± 4.69*
CF, 5  M78.77 ± 3.48*0*17.13 ± 3.52*
10  M80.43 ± 5.00*0*21.73 ± 3.36*
20  M81.20 ± 5.15*0*39.40 ± 5.20*

Values are presented as the mean ± SD ( ). P < 0.01 versus control.