A Metabolomics Profiling Study in Hand-Foot-and-Mouth Disease and Modulated Pathways of Clinical Intervention Using Liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry

Figure 1

OPLS score of healthy control group and HFMD group. The score plot showed that levels of markers in serum of healthy control and HFMD patients were different. (a) Positive ion mode (𝑘=11001, 𝑛=36, 𝑅²𝑌=0.985, 𝑅²𝑋=0.321, 𝑄²=0.947, 𝐴=1+1). (b) Negative ion mode (𝑘=11700, 𝑛=36, 𝑅²𝑌=0.986, 𝑅²𝑋=0.263, 𝑄²=0.931, 𝐴=1+1). Each point represents an individual sample. (Left side, ▲) Samples from HFMD patients. (Right side, ▲) Samples from healthy controls.

(a)

(b)