Inhibited growth of tumor in in situ transplantation tumor model of nude mice Prolonged survival time of hepatoma bearing mice Induced apoptosis through regulating expression of apoptosis-related gene bax and the ratio of bcl-2/bax in situ hepatoma transplantation model and apoptotic characteristics determined by ultrastructure observation
Prohibited growth of transplant hepatoma in rats by intra-tumor injection Inhibited expression of PCNA of transplanted hepatoma in rats Reduced liver toxicity compared to ethanol therapy Induced apoptosis in cancer cell through activation of the Fas/FasL pathway
Inhibited growth of tumors in hepatoma bearing mice Improved phagocytic function of macrophages determined by chicken-red cell phagocytic rate Inhibited proliferation of cancer cells in vitro Induced apoptosis determined by ultrastructure observation of apoptotic cancer cells
Inhibiting growth of tumors in mice bearing human HepG2 tumor and enhancement of chemotherapeutic efficacy when combined with anticancer agents such as CPT-11, capecitabine, doxorubicin, and thalidomide
Rhizoma Dioscoreae, Fructus Crataegi, Fructus Ziziphi Jujubae, etc.
Anticancer
Reduced and delayed the incidence of hepatocellular carcinoma in rats Prolonged survival time of tumor bearing rats Affected process of cancer cell cycle through suppressing overexpression of related modulators