The Inhibitory Effect of 3β-Hydroxy-12-oleanen-27-oic Acid on Growth and Motility of Human Hepatoma HepG2 Cells through JNK and Akt Signaling Pathway
Figure 6
Effect of 3β-hydroxy-12-oleanen-27-oic acid (ATA) on the migration of HepG2 cells. HepG2 cells were plated in a 24-well plate and the confluent monolayers were wounded and then incubated with ATA at the concentrations of 0, 5, 10, and 20 μg/mL in serum-free medium. At 0, 24, 36, and, 48 h after wounding; the cells were photographed under an inverted microscope. The histogram demonstrated the migration rate expressed as a percentage of control (0 μg/mL). The values are presented as means ± SD for three independent experiments. Significant differences with 0 μg/mL were designated as ***.