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Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 685642, 13 pages
Research Article

Antidiabetic Effect and Mode of Action of Cytopiloyne

1Department of Veterinary Medicine, National Chung Hsing University, 402 Taichung, Taiwan
2Agricultural Biotechnology Research Center, Academia Sinica, 128 Academia Road, Section 2, Nankang, 115 Taipei, Taiwan
3Research Center, China Medical University and Hospital, Graduate Institute of Clinical Medical Sciences, China Medical University, 40402 Taichung, Taiwan
4Institute of Zoology, National Taiwan University, 10617 Taipei, Taiwan
5Department of Life Sciences, National Chung Hsing University, 402 Taichung, Taiwan

Received 3 November 2012; Accepted 29 January 2013

Academic Editor: Srinivas Nammi

Copyright © 2013 Cicero Lee-Tian Chang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Description of Figure 1: Effect of GF109203X on PKCα phosphorylation in beta cells.

Description of Table 1: Effect of cytopiloyne on Survival rate of diabetic mice.

Description of Figure 2: Prophylactic effect of cytopiloyne on diabetes in db/db mice.

Description of Figure 3: Effect of cytopiloyne on insulin release in rat islet cells in the absence and presence of glucose.

Description of Figure 4: Regulation of ion channels by cytopiloyne.

  1. Supplementary Materials