Ginsenoside RK3 Prevents Hypoxia-Reoxygenation Induced Apoptosis in H9c2 Cardiomyocytes via AKT and MAPK Pathway
Figure 6
Effects of RK3 on apoptosis induced by H/R. H9c2 cardiomyocytes were pretreated with or without RK3 (25 μg/mL) for 12 h prior to H/R exposure. The internucleosomal DNA fragmentation was determined by TUNEL assay (a). TUNEL apoptotic index was determined by calculating the ratio of TUNEL-positive cells to total cells (b). Caspase-3 activity (units per microgram of protein) was also assayed (c). The results are represented as means ± SD from three independent experiments. # versus control group; * versus H/R-treated cells.
