Rhodiola rosea Impairs Acquisition and Expression of Conditioned Place Preference Induced by Cocaine
Figure 3
Effects of RHO on the expression of cocaine-induced CPP. Mice (-10 per group) were conditioned with Cocaine (Coc 25 mg/kg, IP) and received IG Veh or RHO (15, 20 or 25 mg/kg) 60 min before the post-conditioning test. Bars represent the time in seconds spent in the drug-paired compartment during preconditioning (white) and post-conditioning (black). Values are means ± SEM. **; significant difference in the time spent in preconditioning versus post-conditioning sessions.
