Ameliorative Effects of <i>Acanthopanax trifoliatus</i> on Cognitive and Emotional Deficits in Olfactory Bulbectomized Mice: An Animal Model of Depression and Cognitive Deficits

<table>Effects of tacrine (THA) and ATL on ChAT (a) and muscarinic M<sub>1</sub> receptor (b) mRNA expression levels in the hippocampus of OBX mice. Each data column represents the mean ± SEM (<i>n</i> = 10). *<svg height="11.175" id="M10" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 10.9375 11.175" width="10.9375" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,11.113)"><path d="M619 482q0 -69 -40.5 -119t-96 -72.5t-118.5 -26.5h-44l-70 20l-31 -151q-14 -67 0.5 -83t89.5 -22l-5 -28h-287l8 28q65 7 81.5 22t29.5 83l79 398q12 56 0.5 70.5t-78.5 20.5l7 28h255q108 0 164 -43t56 -125zM524 478q0 141 -146 141q-25 0 -47 -8q-16 -6 -20.5 -13.5
t-10.5 -39.5l-43 -241q37 -13 83 -13q67 0 125.5 45t58.5 129z" id="x1D443"></path></g>
</svg> &lt; 0.05 versus mRNA expression levels in vehicle-treated OBX mice (one-way ANOVA, Dunnett’s method).</table>

Evidence-Based Complementary and Alternative Medicine

fig6

Figure 6

Figure 6: Ameliorative Effects of <i>Acanthopanax trifoliatus</i> on Cognitive and Emotional Deficits in Olfactory Bulbectomized Mice: An Animal Model of Depression and Cognitive Deficits 

Figure 6 | Ameliorative Effects of Acanthopanax trifoliatus on Cognitive and Emotional Deficits in Olfactory Bulbectomized Mice: An Animal Model of Depression and Cognitive Deficits 