ATF3 Protects against LPS-Induced Inflammation in Mice via Inhibiting HMGB1 Expression
Figure 3
ATF3 knockout increased LPS-induced MCP-1 level in the lung tissues of mice. Localization of MCP-1 induced by LPS in the lung tissues of WT and ATF3-KO mice detected by immunofluorescence. A: alveoli. Red arrows show MCP-1 staining of alveolar septa with few neutrophils. Insets show MCP-1 expression in the cytoplasm. Scale bar = 50 μm. MCP-1-positive cells were calculated from 4 fields with a total number of 200 cells counted. Data represent mean SEM (). *, .
